Abstract:Food safety is closely linked with every consumer' health, directly bound up with the life safety and consumption safety. Food security incidents have occurred frequently in China on some important industries necessary for life which involve drugs, dairy products, meat, vegetables, eggs and poultry. Thus, it is imperative to strengthen the food safety supervision. However it is essential to consider the optimal regulation equilibrium between "regulatory costs" and "regulatory gains" . In this paper, the international food safety regulation cost was summarized from the perspective of HACCP system, cost-benefit analysis, output directional distance function model, transaction cost analysis, and food traceability system. On that basis, the inspiration for food safety assurance was presented.